Chronic Urticaria: More Than Just an Itchy Rash
Chronic urticaria (CU), or hives, is a frustrating condition that many people struggle with. While half of the cases have no clear cause, about 20-40% could be linked to an underlying autoimmune issue. This means that the body’s immune system mistakenly attacks itself, sometimes triggering hives by releasing histamine—a chemical that causes itching and swelling.
One particularly concerning type of autoimmune urticaria involves the body developing antibodies against its own IgE receptors, leading to the release of histamine and the onset of hives. But it doesn’t stop there—autoimmune urticaria could also be an early indicator of other autoimmune diseases.
The Connection Between Chronic Urticaria and Autoimmune Diseases
A large study followed nearly 13,000 patients with chronic urticaria over 17 years. The results? People with chronic urticaria are more likely to develop autoimmune conditions like:
- Thyroid Issues: Both underactive and overactive thyroid, along with antibodies that mistakenly attack the thyroid gland.
- Joint Pain and Fatigue: Conditions like rheumatoid arthritis and lupus, where the immune system targets the body’s own tissues.
- Digestive Problems: Celiac disease, which is a severe reaction to gluten.
These conditions often appeared within 10 years of the chronic urticaria diagnosis, making it a potential early warning sign.
What Should Patients with Chronic Urticaria Do?
If your hives last more than six weeks, don’t just ignore them. They could be a sign of something more serious. Not every case leads to another autoimmune disease, but it’s better to be safe. An Allergist/Immunologist can evaluate your symptoms and help you manage your condition before it progresses.
Information You Can Use
- Chronic Urticaria and Autoimmune Link: Chronic urticaria might be an early sign of an autoimmune condition, especially in women.
- Seek Specialist Help: An Allergist/Immunologist can determine if your hives are related to an autoimmune issue.
- Early Intervention is Key: Early diagnosis and treatment can improve your quality of life and help prevent more serious health issues.
If you need help
If you’re dealing with chronic urticaria, don’t wait. Reach out to an Allergist/Immunologist for proper evaluation and care. At the Allergy Immunology Clinic, we’re here to help you find relief.
