Unusual Treatment for Autoimmune-Induced Chronic Urticaria/Hives
If you’ve been battling chronic urticaria (hives) that just won’t go away—even with antihistamines—your immune system might be the hidden culprit.
Research shows that a major trigger of chronic hives is autoimmunity, meaning your body mistakenly activates mast cells in your skin, leading to itching, swelling, and redness that persist for months or even years.
The Two Autoimmune Triggers Behind Chronic Urticaria
🔬 Trigger #1: IgE Reacting to Your Own Body
Your immune system produces IgE antibodies that mistakenly recognize a substance from your own body as an allergen. This activates mast cells, leading to histamine release and hives.
🔬 Trigger #2: Autoantibodies Directly Stimulating Mast Cells
In this case, your body produces antibodies that directly stimulate mast cells—no external allergen involved. The result? Continuous histamine release and chronic hives.
The “Serum Test” – A Shocking Discovery
Scientists have performed a fascinating test:
✅ They took a small amount of blood from a patient with chronic hives
✅ Separated the serum (the liquid part of blood)
✅ Injected a tiny amount of that serum under the patient’s own skin
What happened? The injected area developed hives! This proved that something in the patient’s own serum was triggering mast cells.
But this discovery didn’t just help diagnose autoimmune urticaria—it led to a groundbreaking treatment approach.
An Unusual but Effective Treatment: Using Your Own Serum
In a “fighting fire with fire” method, researchers explored the idea of injecting a patient’s own serum in a controlled way to help the immune system gradually become less reactive.
This approach, known as Autologous Serum Therapy (AST), has shown promising results, especially for patients who:
✅ Do not respond to antihistamines
✅ Want to avoid long-term immune suppression or Biologic medications
✅ Are looking for a potential long-term solution
Studies indicate that patients start seeing results after about eight treatment sessions, with some achieving complete remission.
Why AI Clinic is the Best Place for Chronic Urticaria Treatment
At the Allergy Immunology Clinic, we specialize in treating chronic hives that don’t respond to conventional medications. With our structured Autologous Serum Therapy (AST) protocol, we have helped many patients achieve relief and long-term control.
💡 Want to learn more about this innovative treatment? Check out our full guide:
🔗 Autologous Serum Therapy for Chronic Hives – A New Hope
📞 If chronic hives are affecting your life, book a consultation today!
